Oral Mucosal Immunization with a Particle-mediated Gene Gun in Animals
نویسندگان
چکیده
منابع مشابه
Gene gun-mediated DNA immunization primes development of mucosal immunity against bovine herpesvirus 1 in cattle.
Vaccination by a mucosal route is an excellent approach to the control of mucosally acquired infections. Several reports on rodents suggest that DNA vaccines can be used to achieve mucosal immunity when applied to mucosal tissues. However, with the exception of one study with pigs and another with horses, there is no information on mucosal DNA immunization of the natural host. In this study, th...
متن کاملLip Leishmaniasis with Oral-mucosal Involvement: A Case Report
Statement of the problem: Nowadays leishmaniasis is a common infectious disease around the world which is caused by a protozoan parasite named Leishmania. This parasite is transmitted to human by an infected female sand fly. This disease has three clinical forms; mucosal forms are rare in Iran. Purpose: The purpose of this study was to report a case of leishmaniasis with lip and oral mucosal in...
متن کاملMucosal immunization
Increased immunization coverage, along with improved sanitization and safe water, is the most important public health intervention to improve child health in documented human history, resulting in a significant decrease in child mortality during the 20 century. Immunization is considered by the World Health Organization (WHO) as one of the most cost-effective of all health interventions, having...
متن کاملMucosal immunization: a realistic alternative.
Most infections occur at or through mucosal surfaces. Despite this knowledge, current vaccination practices rely predominantly on parenteral administration with only a few vaccines being registered for administion by the mucosal route. Whilst mucosal immunization brings many advantages, the lack of reliable delivery systems has been a major drawback to date. With the recent advances in delivery...
متن کامل0231 - Gene Gun-mediated Gene Transfer to Intervertebral Disc Cells
INTRODUCTION: Gene therapy using retroviral and, more recently, adenoviral vectors is gaining interest in orthopedics. Particle-mediated gene transfer with a gene gun is a novel non-viral alternative that carries great promise [1]. The basic principle of particle-mediated gene transfer is to use high velocity DNA-coated gold particles that are accelerated by high pressure helium gas to penetrat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oral Medicine & Pathology
سال: 2004
ISSN: 1342-0984,1882-1537
DOI: 10.3353/omp.9.13